Issues we may face for 24*7 Bot?

What are the challenges we may face for a blue prism bot which is running 24*7?
Might be environment issues or VM issues or DB issues? Please share with us how you overcome those?

My turn:
1. Environment issues. VM used to struck while bot is running. due to this bot terminated many times through out the day. might be 10 times max per day.
Work Around we did: Changing/Swapping the VMs. still we have to figure out the better solution. sometimes still facing same issue.

Any help on this would be helpful.
 
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